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Types Of Hyperplasia
There are two forms of thymic hyperplasia: 1- True thymic hyperplasia (or rebound hyperplasia), in which there are normal proportions of glandular/ lymphoid elements in an enlarged gland secondary to rebound following stress-related atrophy, illness, or immune suppression (following chemotherapy or discontinuation of corticosteroid administration) [15,19]. When the body is exposed to stress the thymus may shrink to as little as 40% of its original volume (depending on the severity and duration of the stress) [20]. Once the body recovers, the thymus can usually grows back to its original size within 9 months, but it can grow to be as much as 50% larger [20]. Approximately 10-25% of patient who undergo chemotherapy may develop rebound hyperplasia [20]. Most cases of thymic hyperplasia secondary to chemotherapy occur within a year or two and the gland typically returns to normal size [8,20]. Because of bolstered cell-mediated immunity, thymic hyperplasia has been associated...
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