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Nerves Conduction In Myasthenia Gravis

Electromyogram (EMG) and nerve conduction studies Normal: The EMG recording shows no electrical activity when the muscle is at rest. There is a smooth, wavy line on the recording with each muscle contraction. The nerve conduction studies show that the nerves send electrical impulses to the muscles or along the sensory nerves at normal speeds, or conduction velocities. Sensory nerves allow the  brain  to feel pain, touch, temperature, and vibration. Not all nerves have the same normal conduction velocities. They generally get slower as a person gets older. Abnormal: Electrical activity in a muscle at rest shows that there may be a problem with the nerves used by the muscle. Abnormal wave lines when a muscle contracts may mean there is a muscle or nerve problem. Examples include a  herniated disc ,  amyotrophic lateral sclerosis  (ALS), and  inflammation . In nerve conduction studies, the speed of nerve impulses is slower than normal for that ...
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Nerve Conduction Study

In this test, several flat metal-disc electrodes are attached to your skin with tape or a paste. An electrode that puts out electric pulses is placed right over the nerve. Then a recording electrode is placed over the muscles controlled by that nerve. Several quick electrical pulses are given to the nerve. The time it takes for the muscle to contract in response to the electrical  pulse  is recorded. The speed of the response is called the conduction velocity. The same nerves on the other side of the body may be studied. The results from both sides of the body can be compared. When the test is done, the electrodes are removed. Nerve conduction studies are done before an EMG if both tests are being done. Nerve conduction tests may take from 15 minutes to 1 hour or more. How long the tests take depends on how many nerves and muscles are studied.
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Nuclear Imaging

Thallium-201 ( 201  Tl) single photon emission CT (SPECT) scanning is useful for the evaluation of thymic lesions associated with myasthenia gravis, including lymphoid follicular hyperplasia and thymoma.  [ 12 ]  On early images, 201  Tl accumulation is more intense in thymomas than in the normal thymus and in lymphoid follicular hyperplasia. On delayed images, uptake is more intense in thymoma and in lymphoid follicular hyperplasia than in the normal thymus. Therefore, 201  Tl SPECT scanning can be used to differentiate normal thymus from lymphoid follicular hyperplasia and thymoma in patients with myasthenia gravis. Degree of confidence 201  Tl uptake is considered to reflect various factors, including cellular metabolic activity, regional blood flow, and the number of viable cells in the lesion; hence, 201  Tl imaging is in some respects superior to CT scanning
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